成員介紹

Selected recent publications (Pubmed Search)
(† Contributed equally to the article; * Correspondence author of the article)

Lee WC, Leu S, Su CH, Tain YL, Wu KLH, Hsu CN, Tzeng HT*. Tadalafil Ameliorates Chronic Ischemia-Associated Bladder Overactivity in Fructose-Fed Rats by Exerting Pelvic Angiogenesis and Enhancing p-eNOS Expression. International Journal of Molecular Sciences, 26(3):1363 (2025)

Tzeng HT, Lee WC. Impact of Transgenerational Nutrition on Nonalcoholic Fatty Liver Disease Development: Interplay between Gut Microbiota, Epigenetics and Immunity. Nutrients, 16(9):1388 (2024)

Tzeng HT, Huang YJ. Tumor Vasculature as an Emerging Pharmacological Target to Promote Anti-Tumor Immunity. International Journal of Molecular Sciences, 24(5):4422 (2023)

Tzeng HT, Chyuan IT*, Lai JH*. Targeting the JAK-STAT pathway in autoimmune diseases and cancers: A focus on molecular mechanisms and therapeutic potential. Biochemical Pharmacology, 193:114760 (2021)

Tzeng HT, Chyuan IT*. Immunometabolism in systemic lupus erythematosus: Relevant pathogenetic mechanisms and potential clinical applications. Journal of the Formosan Medical Association, 120(9):1667-1675 (2021)

Tzeng HT, Yang JL, Tseng YJ, Lee CH, Chen WJ, Chyuan IT. Plasminogen Activator Inhibitor-1 Secretion by Autophagy Contributes to Melanoma Resistance to Chemotherapy through Tumor Microenvironment Modulation. Cancers, 13(6):1253 (2021)

Tseng YJ, Lee CH, Chen WY, Yang JL, Tzeng HT*. Inhibition of PAI-1 Blocks PD-L1 Endocytosis and Improves the Response of Melanoma Cells to Immune Checkpoint Blockade. Journal of Investigative Dermatology, 141(11):2690-2698.e6 (2021)

Peng JM, Chen WY, Cheng JH, Luo JW, Tzeng HT*. Dysregulation of Cytoskeleton Remodeling Drives Invasive Leading Cells Detachment. Cancers, 13(22):5648 (2021)

Chen WY, Li LC, Wu YH, Yang JL, Tzeng HT*. Emerging Roles of Interleukin-33-responsive Kidney Group 2 Innate Lymphoid Cells in Acute Kidney Injury. International Journal of Molecular Sciences, 21(4):1544 (2020)

Tzeng HT, Chyuan IT, Chen WY. Shaping of Innate Immune Response by Fatty Acid Metabolite Palmitate. Cells, 8(12):1633 (2019)

EDUCATION:

2007 – 2014 Ph.D.
Graduate Institute of Immunology, College of Medicine,
National Taiwan University, Taipei, Taiwan

PROFESSIONAL EXPERIENCE:

2018/8 ~ present   Assistant Professor
Institute for Translational Research in Biomedicine,
Kaohsiung Chang Gung Memorial Hospital,
Kaohsiung, Taiwan

2014/8 ~ 2018/7   Postdoctoral Research Fellow
Department of Pharmacology, College of Medicine,
National Cheng Kung University, Tainan, Taiwan

AWARDS AND RESEARCH SUPPORT:

2017  The third Prize (oral presentation in English), Autumn Camp 2017, The Taiwan Society for
Biochemistry and Molecular Biology
2017  The Second Prize (Thematic oral presentation), 32th Joint Annual Conference of Biomedical
Science (JACBS)
2016  The First Prize (oral presentation), 31th Annual Meeting of Toxicology Society of Taiwan
2016  Travel Grant, International Academic Conference, Ministry of Science and Technology
2012  Travel Grant, Oversea International Academic Conference, Ministry of Education
2012  Travel Grant, aim for the top University Project to the National Taiwan University
2012  Excellent paper Award (oral presentation), The Chinese Society of Immunology
2011  Excellent paper Award (oral presentation), The Chinese Society of Immunology
2010  Excellent paper Award (oral presentation), The Chinese Society of Immunology

RESEARCH INTERESTS:

1. Viral immunology of infectious disease
2. Regulation of T cell activation in cancer
3. Development of immunotherapy for cancer treatment