• 2024 Frontiers in Translational Medicine


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  • Institute for Translational Research in Biomedicine

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About ITRBM

Translational research in biomedicine transcends the boundaries between bench and bedside research. It is the synthesis of ideas, technologies and research outcomes that are associated with a particular health theme.
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Our Members

The governing philosophy of the ITRBM is that clinical and laboratory scientists must work together with an ultimate objective to tackle health-oriented problems.
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Contact Us

Address:
11th Floor, Children’s Building; No.123 Da-Pi Road, Niaosong District, Kaohsiung City, Taiwan
Phone:
+886-7-731-7123 #8099/#8599
E-mail:
contact.itrbm@gmail.com
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Research Highlights

Julie Y.H. Chan, PhD

Biomedicines. 2022 Oct; 10(11):2716.
Vinpocetine Ameliorates Metabolic-Syndrome-Associated Bladder Overactivity in Fructose-Fed Rats by Restoring Succinate-Modulated cAMP Levels and Exerting Anti-Inflammatory Effects in the Bladder Detrusor Muscle.

Hon-Kan Yip, MD

Biomed J. 2024 Apr; 47(2): 100613.
Repeated administration of adipose-derived mesenchymal stem cells added on beneficial effects of empagliflozin on protecting renal function in diabetic kidney disease rat.
 

You-Lin Tain, MD

Am J Kidney Dis. 2024 Mar; S0272-6386(24)00669-3.
 
Gestational Exposure to Maternal Systemic Glucocorticoids and Childhood Risk of CKD.

Chiung-Chih Chang, MD PhD

Psychiatry Clin Neurosci. 2023 Jul; 77(7):401-409.
Gray matter reserve determines glymphatic system function in young-onset Alzheimer’s disease: Evidenced by DTI-ALPS and compared with age-matched controls.

Pei-Hsun Sung, MD

Stem Cells Transl Med. 2024 Jun; szae034.
Synergic effect of combined xenogeneic mesenchymal stem cells and ceftriaxone on acute septic arthritis.

Kay L.H. Wu, PhD

J Nutr Biochem. 2024 Apr; 126: 109571.
Butyrate reduction and HDAC4 increase underlie maternal high fructose-induced metabolic dysfunction in hippocampal astrocytes in female rats.

Jenq-Lin Yang, PhD

Eur J Pharmacol. 2023 Jan; 938: 175439.
Alternative role of glucagon-like Peptide-1 receptor agonists in neurodegenerative diseases.

Steve Leu, PhD

BMC Cardiovasc Disord. 2024 May; 24(1): 287.
Cardiomyocyte-specific overexpression of GPR22 ameliorates cardiac injury in mice with acute myocardial infarction.
 

Lung-Chih Li, MD PhD

Parmaceuticals. 2023 FEb; 16(2): 222.
Denosumab Is Superior to Raloxifene in Lowering Risks of Mortality and Ischemic Stroke in Osteoporotic Women.

Ching-Yi Tsai, PhD

Neurochem Int. 2024 Sep; 178: 105800.
Astrocyte-secreted lipocalin-2 elicits bioenergetic failure-induced neuronal death that is causally related to high fatality in a mouse model of hepatic encephalopathy.

Kuang-Tzu Huang, PhD

Cell Calcium. 2024 Jul; 121: 102895.
Calreticulin regulates hepatic stellate cell activation through modulating TGF-beta-induced Smad signaling.

Ding-Wei Chen, PhD

Front Immunol. 2022 Sep; 13: 995886.
Comparable bidirectional neutrophil immune dysregulation between Kawasaki disease and severe COVID-19.

Hong-Tai Tzeng, PhD

Nutrients. 2024 May; 16(9): 1388.
Impact of Transgenerational Nutrition on Nonalcoholic Fatty Liver Disease Development: Interplay between Gut Microbiota, Epigenetics and Immunity.

Jei-Ming Peng, PhD

Biochem Pharmacol. 2023 Sep; 215: 115731.
Lymph node metastasis and tumor-educated immune tolerance: Potential therapeutic targets against distant metastasis.