{"id":1988,"date":"2019-06-22T11:46:58","date_gmt":"2019-06-22T03:46:58","guid":{"rendered":"https:\/\/itrbm.org\/tw\/?page_id=1988"},"modified":"2025-06-09T15:48:34","modified_gmt":"2025-06-09T07:48:34","slug":"yang-jl","status":"publish","type":"page","link":"https:\/\/itrbm.org\/tw\/members\/yang-jl\/","title":{"rendered":"\u694a\u653f\u9716 \u6559\u6388"},"content":{"rendered":"<div id='av_section_1' class='avia-section main_color avia-section-large avia-no-border-styling avia-full-stretch av-section-color-overlay-active avia-bg-style-scroll  avia-builder-el-0  el_before_av_one_fourth  avia-builder-el-first   container_wrap sidebar_left' style='background-repeat: no-repeat; background-image: url(https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/03\/dna-1.jpg);background-attachment: scroll; background-position: center center;  '  data-section-bg-repeat='stretch'><div class='av-section-color-overlay-wrap'><div class='av-section-color-overlay' style='opacity: 0.2; background-color: #000000; '><\/div><div class='container' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-small units'><div class='post-entry post-entry-type-page post-entry-1988'><div class='entry-content-wrapper clearfix'>\n<div style='padding-bottom:10px; color:#ffffff;font-size:44px;' class='av-special-heading av-special-heading-h1 custom-color-heading blockquote modern-quote modern-centered  avia-builder-el-1  avia-builder-el-no-sibling  av-inherit-size '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >\u6210\u54e1\u4ecb\u7d39<\/h1><div class='special-heading-border'><div class='special-heading-inner-border' style='border-color:#ffffff'><\/div><\/div><\/div>\n<\/div><\/div><\/main><!-- close content main element --><\/div><\/div><\/div><div id='after_section_1' class='main_color av_default_container_wrap container_wrap sidebar_left' style=' '  ><div class='container' ><div class='template-page content  av-content-small units'><div class='post-entry post-entry-type-page post-entry-1988'><div class='entry-content-wrapper clearfix'>\n<div class=\"flex_column av_one_fourth  flex_column_div av-zero-column-padding first  avia-builder-el-2  el_after_av_section  el_before_av_one_fourth  avia-builder-el-first  \" style='border-radius:0px; '><div class='avia-image-container  av-styling-    avia-builder-el-3  avia-builder-el-no-sibling  avia-align-left '  itemprop=\"ImageObject\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  ><div class='avia-image-container-inner'><div class='avia-image-overlay-wrap'><img class='avia_image' src='https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2025\/05\/9B2A2499-YangJL_240.jpg' alt='' title='9B2A2499 YangJL 240' height=\"240\" width=\"180\"  itemprop=\"thumbnailUrl\"  \/><\/div><\/div><\/div><\/div>\n<div class=\"flex_column av_one_fourth  flex_column_div av-zero-column-padding   avia-builder-el-4  el_after_av_one_fourth  el_before_av_one_half  \" style='border-radius:0px; '><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock  '   itemprop=\"text\" ><h3><strong><span style=\"font-size: 20px; color: #109bc5;\">\u694a\u653f\u9716<\/span><\/strong><br \/>\n<span style=\"font-size: 16px; color: #333333;\">\u6559\u6388<\/span><\/h3>\n<h5><span style=\"color: #333333;\">\u7d30\u80de\u548c\u5206\u5b50\u795e\u7d93\u79d1\u5b78<\/span><br \/>\n<span style=\"color: #333333;\">\u795e\u7d93\u7d30\u80de DNA \u4fee\u5fa9<\/span><br \/>\n<span style=\"color: #333333;\">\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u75c5\u7406\u751f\u7406\u5b78<\/span><br \/>\n<span style=\"color: #333333;\">\u7f3a\u8840\u6027\u4e2d\u98a8\u4e4b\u6cbb\u7642\u8207\u6a5f\u5236<\/span><\/h5>\n<\/div><\/section><\/div>\n<div class=\"flex_column av_one_half  flex_column_div av-zero-column-padding   avia-builder-el-6  el_after_av_one_fourth  el_before_av_hr  \" style='border-radius:0px; '><div class='avia-icon-list-container   avia-builder-el-7  avia-builder-el-no-sibling '><ul class='avia-icon-list avia-icon-list-left av-iconlist-small avia_animate_when_almost_visible avia-iconlist-animate'>\n<li><div  style='font-size:14px; ' class='iconlist_icon  avia-font-entypo-fontello'><span class='iconlist-char ' aria-hidden='true' data-av_icon='\ue854' data-av_iconfont='entypo-fontello'><\/span><\/div><article class=\"article-icon-entry \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='iconlist_content_wrap'><header class=\"entry-content-header\"><div class='av_iconlist_title iconlist_title_small  '  itemprop=\"headline\"   style='font-size:14px; '>\u806f\u7d61\u96fb\u8a71<\/div><\/header><div class='iconlist_content  '  itemprop=\"text\"  ><h5>(07) 731-7123 ext 8593<\/h5>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><div class='iconlist-timeline'><\/div><\/li>\n<li><div  style='font-size:14px; ' class='iconlist_icon  avia-font-entypo-fontello'><span class='iconlist-char ' aria-hidden='true' data-av_icon='\ue805' data-av_iconfont='entypo-fontello'><\/span><\/div><article class=\"article-icon-entry \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='iconlist_content_wrap'><header class=\"entry-content-header\"><div class='av_iconlist_title iconlist_title_small  '  itemprop=\"headline\"   style='font-size:14px; '>\u96fb\u5b50\u90f5\u4ef6\u4fe1\u7bb1<\/div><\/header><div class='iconlist_content  '  itemprop=\"text\"  ><h5>jyang@cgmh.org.tw<\/h5>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><div class='iconlist-timeline'><\/div><\/li>\n<\/ul><\/div><\/div>\n<div style='height:20px' class='hr hr-invisible   avia-builder-el-8  el_after_av_one_half  el_before_av_tab_container '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div>\n<div class=\"tabcontainer   top_tab   avia-builder-el-9  el_after_av_hr  avia-builder-el-last \">\n\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div aria-controls=\"tab-id-1\" role=\"tab\" tabindex=\"0\" data-fake-id=\"#tab-id-1\" class=\"tab active_tab\"  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue864' data-av_iconfont='entypo-fontello'><\/span>\u7814\u7a76\u7c21\u4ecb<\/div>\n    <div id=\"tab-id-1-container\" class=\"tab_content active_tab_content\" aria-hidden=\"false\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<p>\u63a2\u8a0e\u6d89\u53ca\u8abf\u63a7\u795e\u7d93\u7d30\u80de\u548c\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u4e2dDNA\u4fee\u5fa9\u86cb\u767d\u7684\u4fe1\u865f\u6a5f\u8f49\u662f\u5be6\u9a57\u5ba4\u904e\u53bb\u6578\u5e74\u7684\u7814\u7a76\u4e3b\u8ef8\u3002\u6211\u5011\u7684\u76ee\u6a19\u662f\u70ba\u4e86\u89e3\u8870\u8001\u3001\u795e\u7d93\u5931\u8abf\u548c\u7f3a\u8840\u6027\u4e2d\u98a8\u7b49\u904e\u7a0b\u4e2d\u7522\u751fDNA\u640d\u50b7\u7684\u81f4\u75c5\u56e0\u5b50\u7684\u6a5f\u5236\uff0c\u7136\u5f8c\u901a\u904e\u63d0\u9ad8DNA\u4fee\u5fa9\u6548\u7387\u4f86\u61c9\u5c0dDNA\u640d\u50b7\u4ee5\u589e\u52a0\u795e\u7d93\u7d30\u80de\u5b58\u6d3b\u3002\u958b\u767c\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u7684\u6cbb\u7642\u65b9\u6cd5\u662f\u6211\u5011\u5be6\u9a57\u5ba4\u7684\u6700\u7d42\u76ee\u6a19\u3002<\/p>\n<p>\u76ee\u524d\uff0c\u6211\u7684\u5be6\u9a57\u5ba4\u4ea6\u5354\u52a9\u6216\u8207\u91ab\u751f\u5408\u4f5c\u767c\u5c55\u65b0\u7684\u5be6\u9a57\u548c\u8a08\u756b\uff0c\u8a66\u5716\u5c07\u795e\u7d93\u9000\u5316\u6027\u75be\u75c5\u3001\u5927\u8166\u7f3a\u8840\u6027\u4e2d\u98a8\u3001\u8840\u7ba1\u548c\u814e\u6027\u8a8d\u77e5\u75c5\u8b8a\u9818\u57df\u7684\u57fa\u790e\u7814\u7a76\u5de5\u4f5c\u8207\u7684\u81e8\u5e8a\u6cbb\u7642\u806f\u7e6b\u8d77\u4f86\u3002 \u6b64\u5916\uff0c\u6d89\u53ca\u795e\u7d93\u767c\u708e\u7684\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u548c\u7dda\u7c92\u9ad4\u529f\u80fd\u969c\u7919\u4e5f\u662f\u76ee\u524d\u7684\u7814\u7a76\u76ee\u6a19\u3002<\/p>\n<h4><strong>\u7d93\u7531\u63d0\u9ad8APE1\u8868\u73fe\u800c\u63d0\u9ad8\u795e\u7d93\u7d30\u80de\u6c27\u5316DNA\u4fee\u5fa9\u6548\u7387<\/strong><\/h4>\n<p><a href=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/APE1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-1992\" src=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/APE1-495x400.png\" alt=\"\" width=\"300\" height=\"213\" srcset=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/APE1-300x213.png 300w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/APE1.png 608w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/APE1-260x185.png 260w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/APE1-450x320.png 450w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\u4e0d\u518d\u6709\u7d72\u5206\u88c2\u7684\u795e\u7d93\u7d30\u80de\u662f\u9ad8\u5ea6\u5206\u5316\u7684\u7d30\u80de\uff0c\u5176\u8868\u73fe\u51fa\u7d93\u5e38\u6027\u8208\u596e\u6027\u96fb\u4f4d\u8a0a\u865f\u50b3\u905e\u3001\u9ad8\u4ee3\u8b1d\u7387\u548c\u5927\u91cf\u7684\u8f49\u9304\u6d3b\u6027\u3002\u9019\u4e9b\u7d30\u80de\u4e2d\u7684\u9ad8\u4ee3\u8b1d\u6d3b\u6027\u7522\u751f\u76f8\u5c0d\u5927\u91cf\u7684\u6d3b\u6027\u6c27\u7269\u8cea (ROS)\uff0c\u5176\u53ef\u7834\u58de\u8102\u8cea\u3001\u86cb\u767d\u8cea\u548cDNA\u3002\u7531\u65bc\u795e\u7d93\u7d30\u80de\u4ee3\u8b1d\u7387\u8f03\u9ad8\uff0c\u5176\u53d7\u5230\u6c27\u5316\u53cd\u61c9\u7684\u523a\u6fc0\u800c\u7522\u751f\u6c27\u5316\u6027DNA\u640d\u50b7\u3002\u7d30\u80de\u6838DNA\u548c\u7dda\u7c92\u9ad4DNA\u4e2d\uff0c\u6c27\u5316\u6027DNA\u640d\u50b7\u7684\u7d2f\u7a4d\u662f\u795e\u7d93\u9000\u5316\u6027\u75be\u75c5\u548c\u6b63\u5e38\u8870\u8001\u7684\u75c5\u539f\u9ad4\u3002\u56e0\u6b64\uff0cDNA\u4fee\u5fa9\u80fd\u529b\u5c0d\u795e\u7d93\u7d30\u80de\u7684\u6b63\u5e38\u529f\u80fd\u548c\u5b58\u6d3b\u81f3\u95dc\u91cd\u8981\u3002 \u9e7c\u57fa\u5207\u9664\u4fee\u5fa9\uff08BER\uff09\u9014\u5f91\u901a\u5e38\u88ab\u8a8d\u70ba\u662f\u4fee\u5fa9DNA\u7684\u6c27\u5316\u640d\u50b7\u3001\u812b\u6c28\u3001\u70f7\u57fa\u5316\u548c\u55ae\u93c8\u65b7\u88c2\u7684\u4e3b\u8981\u6a5f\u5236\uff0c\u5176\u6d89\u53ca\u591a\u7a2e\u9175\u7d20\u548c\u8def\u5f91\u904e\u7a0b\uff0c\u4f8b\u5982DNA\u7cd6\u57fa\u5316\u9176\u3001\u812b\u560c\u5464\/\u812b\u5627\u5576\u6838\u9178\u5167\u5207\u91761(APE1)\u3001DNA\u805a\u5408\u9176\u03b2\u548c\u9023\u63a5\u9176\u3002\u6211\u5011\u4e4b\u524d\u7684\u7814\u7a76\u986f\u793a\uff0cAPE1\u80fd\u5920\u7d93\u7531\u6c27\u5316\u53cd\u61c9\u3001\u795e\u7d93\u905e\u8cea(\u8c37\u6c28\u9178)\u3001\u8166\u6e90\u6027\u795e\u7d93\u71df\u990a\u56e0\u5b50\uff08BDNF\uff09\u548c\u985e\u6607\u7cd6\u7d20\u80dc\u80bd-1 (GLP-1) \u800c\u589e\u5f37\uff0c\u4ee5\u63d0\u9ad8DNA\u4fee\u5fa9\u6548\u7387\uff0c\u4e26\u975eBER\u7684\u5176\u4ed6\u4fee\u5fa9\u9176\u3002\u6211\u5011\u7684\u7814\u7a76\u767c\u73fe\u6c27\u5316\u53cd\u61c9\u3001\u8c37\u6c28\u9178\u3001BDNF\u548cGLP-1\u7684\u6240\u6709\u4e0b\u6e38\u4fe1\u865f\u50b3\u5c0e\u90fd\u671d\u5411CaMK-CREB\u6216Akt-CREB\u8a0a\u865f\u93c8\u4ee5\u589e\u5f37APE1\u4e4b\u8868\u73fe\u3002\u6211\u5011\u63d0\u51faCREB\u4fe1\u865f\u50b3\u905e\u93c8\u70ba\u63d0\u9ad8APE1\u8868\u73fe\u548c\u6c27\u5316DNA\u4fee\u5fa9\u6548\u7387\u7684\u91cd\u8981\u9014\u5f91\uff0c\u53ef\u4f5c\u70ba\u795e\u7d93\u9000\u884c\u6027\u75be\u75c5\u3001\u7f3a\u8840\u6027\u4e2d\u98a8\u3001\u7672\u7647\u767c\u4f5c\u548c\u8a31\u591a\u5176\u4ed6\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u7684\u6cbb\u7642\u65b9\u5411\u3002<\/p>\n<h4><strong>\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u5728\u7f3a\u8840\u6027\u4e2d\u98a8\u6cbb\u7642\u4e2d\u7684\u89d2\u8272<\/strong><\/h4>\n<p><a href=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/Astrocyte.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-1993\" src=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/Astrocyte-495x400.png\" alt=\"\" width=\"300\" height=\"187\" srcset=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/Astrocyte-300x187.png 300w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/Astrocyte-768x479.png 768w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/Astrocyte-705x440.png 705w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/Astrocyte-450x281.png 450w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/Astrocyte.png 800w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a>\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u662f\u54fa\u4e73\u52d5\u7269\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\uff08CNS\uff09\u4e2d\u6700\u8c50\u5bcc\u7684\u7d30\u80de\uff0c\u4e26\u4e14\u5728\u7dad\u6301\u52d5\u614b\u5e73\u8861\u548c\u5927\u8166\u6b63\u5e38\u529f\u80fd\u65b9\u9762\u767c\u63ee\u591a\u91cd\u4f5c\u7528\u3002\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u7684\u7d30\u80de\u548c\u5206\u5b50\u5167\u5bb9\u7269\u3001\u5f62\u614b\u548c\u529f\u80fd\u6703\u53d7\u5404\u7a2eCNS\u640d\u50b7\u800c\u6539\u8b8a\uff0c\u800c\u88ab\u7a31\u70ba\u201c\u53cd\u61c9\u6027\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u201d\u3002\u53cd\u61c9\u6027\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u7684\u4f5c\u7528\u5c1a\u672a\u660e\u78ba\u5b9a\u7fa9\uff0c\u5176\u5c0dCNS\u640d\u50b7\u5f8c\u7684\u6062\u5fa9\u6709\u597d\u6709\u58de\u3002\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u7684\u6240\u6709\u751f\u7406\u548c\u7d30\u80de\u7279\u6027\u5305\u62ec\u8010\u7f3a\u6c27\u3001\u5206\u6ccc\u795e\u7d93\u71df\u990a\u56e0\u5b50\u3001\u6297\u8208\u596e\u6027\u6bd2\u6027\u3001\u795e\u7d93\u81a0\u8cea\u7622\u75d5\u5f62\u6210\u3001\u4ecb\u5c0e\u795e\u7d93\u7d30\u80de\u751f\u6210\u548c\u7a81\u89f8\u751f\u6210\u3001\u589e\u5f37\u8840\u7ba1\u751f\u6210\u3001\u7dad\u6301BBB\u529f\u80fd\u7b49\uff0c\u90fd\u986f\u793a\u51fa\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u662f\u7f3a\u8840\u6027\u4e2d\u98a8\u3001\u751a\u81f3\u5176\u4ed6\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u7684\u6f5b\u5728\u6cbb\u7642\u6a19\u7684\u3002\u6211\u5011\u76ee\u524d\u7684\u7814\u7a76\u5df2\u7d93\u89c0\u5bdf\u5230\u7f3a\u8840\u6027\u4e2d\u98a8\u5468\u908a\u5340 (penumbral area) \u7684\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u80fd\u5920\u8f49\u5206\u5316\u6210\u653e\u5c04\u72c0\u81a0\u8cea\u7d30\u80de\uff0c\u6211\u5011\u6b63\u5728\u7814\u7a76\u6d89\u53ca\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u5b58\u6d3b\u548c\u8f49\u5206\u5316\u7684\u53ef\u80fd\u6a5f\u5236\u3002\u63d0\u9ad8\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u6d3b\u529b\u4e26\u6709\u6548\u8abf\u7bc0\u53cd\u61c9\u6027\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u5c0d\u7f3a\u8840\u6027\u4e2d\u98a8\u5f8c\u7684\u6709\u76ca\u5f71\u97ff\u53ef\u80fd\u662f\u958b\u767c\u6cbb\u7642\u65b9\u6cd5\u7684\u65b0\u65b9\u5411\u3002<\/p>\n\n        <\/div>\n    <\/div>\n<\/section>\n\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div aria-controls=\"tab-id-2\" role=\"tab\" tabindex=\"0\" data-fake-id=\"#tab-id-2\" class=\"tab \"  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue836' data-av_iconfont='entypo-fontello'><\/span>\u5b78\u8853\u8457\u4f5c<\/div>\n    <div id=\"tab-id-2-container\" class=\"tab_content \" aria-hidden=\"true\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<p><strong>Recent publications (<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Yang%2C+Jenq+Lin%5Bauthor%5D\" target=\"_blank\" rel=\"noopener\">Pubmed Search<\/a>)<\/strong><\/p>\n<p>1: Wong LS, Yang JL, Yen YT, Lee CH, Yang JH. Endothelin-1 Participates in the<br \/>\nPathogenesis of Prurigo Nodularis by Promoting NGF Expression via Endothelial<br \/>\nReceptor B in Epidermal Keratinocytes and Dorsal Root Ganglion Cells. Allergy.<br \/>\n2025 May;80(5):1530-1533. doi: 10.1111\/all.16564. Epub 2025 Apr 18. PMID:<br \/>\n40249388; PMCID: PMC12105065.<\/p>\n<p>2: Pe LS, Pe KCS, Panmanee J, Govitrapong P, Yang JL, Mukda S. Plausible<br \/>\ntherapeutic effects of melatonin and analogs in the dopamine-associated<br \/>\npathophysiology of bipolar disorder. J Psychiatr Res. 2025 Feb;182:13-20. doi:<br \/>\n10.1016\/j.jpsychires.2024.12.046. Epub 2025 Jan 2. PMID: 39793267.<\/p>\n<p>3: Yang JL, Lin WL, Tai SB, Ciou YS, Chung CL, Chen JJ, Liu PF, Lin MW, Chen CL.<br \/>\nSuppression of TGF\u03b2-Induced Interleukin-6 Secretion by Sinulariolide from Soft<br \/>\nCorals through Attenuation of the p38-NF-kB Pathway in Carcinoma Cells. Int J<br \/>\nMol Sci. 2023 Jul 19;24(14):11656. doi: 10.3390\/ijms241411656. PMID: 37511415;<br \/>\nPMCID: PMC10380600.<\/p>\n<p>4: Chen CY, Chao YM, Cho CC, Chen CS, Lin WY, Chen YH, Cassar M, Lu CS, Yang JL,<br \/>\nChan JYH, Juo SH. Cerebral Semaphorin3D is a novel risk factor for age-<br \/>\nassociated cognitive impairment. Cell Commun Signal. 2023 Jun 14;21(1):140. doi:<br \/>\n10.1186\/s12964-023-01158-5. PMID: 37316917; PMCID: PMC10265764.<\/p>\n<p>5: Chen SD, Chuang YC, Lin TK, Yang JL. Alternative role of glucagon-like<br \/>\nPeptide-1 receptor agonists in neurodegenerative diseases. Eur J Pharmacol. 2023<br \/>\nJan 5;938:175439. doi: 10.1016\/j.ejphar.2022.175439. Epub 2022 Dec 2. PMID:<br \/>\n36470445.<\/p>\n<p>6: Huang CC, Chou CA, Chen WY, Yang JL, Lee WC, Chen JB, Lee CT, Li LC.<br \/>\nEmpagliflozin Ameliorates Free Fatty Acid Induced-Lipotoxicity in Renal Proximal<br \/>\nTubular Cells via the PPAR\u03b3\/CD36 Pathway in Obese Mice. Int J Mol Sci. 2021 Nov<br \/>\n17;22(22):12408. doi: 10.3390\/ijms222212408. PMID: 34830289; PMCID: PMC8621539.<\/p>\n<p>7: Huang CY, Yang JL, Chen JJ, Tai SB, Yeh YH, Liu PF, Lin MW, Chung CL, Chen<br \/>\nCL. Fluoroquinolones Suppress TGF-\u03b2 and PMA-Induced MMP-9 Production in Cancer<br \/>\nCells: Implications in Repurposing Quinolone Antibiotics for Cancer Treatment.<br \/>\nInt J Mol Sci. 2021 Oct 27;22(21):11602. doi: 10.3390\/ijms222111602. PMID:<br \/>\n34769032; PMCID: PMC8584204.<\/p>\n<p>8: Chen SD, Yang JL, Hsieh YH, Lin TK, Lin YC, Chao AC, Yang DI. Potential Roles<br \/>\nof Sestrin2 in Alzheimer&#8217;s Disease: Antioxidation, Autophagy Promotion, and<br \/>\nBeyond. Biomedicines. 2021 Sep 24;9(10):1308. doi: 10.3390\/biomedicines9101308.<br \/>\nPMID: 34680426; PMCID: PMC8533411.<\/p>\n<p>9: Chang CC, Silva BBI, Huang HY, Tsai CY, Flores RJD, Tayo LL, Tyan YC, Tsai<br \/>\nMA, Catulin GEM, Chuang KP, Yang JL. Development and Validation of KASP Assays<br \/>\nfor the Genotyping of Racing Performance-Associated Single Nucleotide<br \/>\nPolymorphisms in Pigeons. Genes (Basel). 2021 Sep 3;12(9):1383. doi:<br \/>\n10.3390\/genes12091383. PMID: 34573366; PMCID: PMC8468996.<\/p>\n<p>10: Li LC, Chen WY, Chen JB, Lee WC, Chang CC, Tzeng HT, Huang CC, Chang YJ,<br \/>\nYang JL. The AST-120 Recovers Uremic Toxin-Induced Cognitive Deficit via NLRP3<br \/>\nInflammasome Pathway in Astrocytes and Microglia. Biomedicines. 2021 Sep<br \/>\n17;9(9):1252. doi: 10.3390\/biomedicines9091252. PMID: 34572437; PMCID:<br \/>\nPMC8467651.<\/p>\n<p>11: Tseng YJ, Lee CH, Chen WY, Yang JL, Tzeng HT. Inhibition of PAI-1 Blocks<br \/>\nPD-L1 Endocytosis and Improves the Response of Melanoma Cells to Immune<br \/>\nCheckpoint Blockade. J Invest Dermatol. 2021 Nov;141(11):2690-2698.e6. doi:<br \/>\n10.1016\/j.jid.2021.03.030. Epub 2021 May 14. PMID: 34000287.<\/p>\n<p>12: Tzeng HT, Yang JL, Tseng YJ, Lee CH, Chen WJ, Chyuan IT. Plasminogen<br \/>\nActivator Inhibitor-1 Secretion by Autophagy Contributes to Melanoma Resistance<br \/>\nto Chemotherapy through Tumor Microenvironment Modulation. Cancers (Basel). 2021<br \/>\nMar 12;13(6):1253. doi: 10.3390\/cancers13061253. PMID: 33809137; PMCID:<br \/>\nPMC7999393.<\/p>\n<p>13: Tsai YH, Su CH, Lee IN, Yang JT, Lin LC, Huang YC, Yang JL. Effects of Early<br \/>\nRehydration on Brain Perfusion and Infarct Core after Middle Cerebral Artery<br \/>\nOcclusion in Rats. Brain Sci. 2021 Mar 29;11(4):439. doi:<br \/>\n10.3390\/brainsci11040439. PMID: 33805440; PMCID: PMC8066368.<\/p>\n<p>14: Chen WY, Wu YH, Tsai TH, Li RF, Lai AC, Li LC, Yang JL, Chang YJ. Group 2<br \/>\ninnate lymphoid cells contribute to IL-33-mediated alleviation of cardiac<br \/>\nfibrosis. Theranostics. 2021 Jan 1;11(6):2594-2611. doi: 10.7150\/thno.51648.<br \/>\nPMID: 33456562; PMCID: PMC7806479.<\/p>\n<p>15: Veschsanit N, Yang JL, Ngampramuan S, Viwatpinyo K, Pinyomahakul J, Lwin T,<br \/>\nChancharoen P, Rungruang S, Govitrapong P, Mukda S. Melatonin reverts<br \/>\nmethamphetamine-induced learning and memory impairments and hippocampal<br \/>\nalterations in mice. Life Sci. 2021 Jan 15;265:118844. doi:<br \/>\n10.1016\/j.lfs.2020.118844. Epub 2020 Dec 2. PMID: 33278389.<\/p>\n<p>16: Yang JL, Lin YT, Chen WY, Yang YR, Sun SF, Chen SD. The Neurotrophic<br \/>\nFunction of Glucagon-Like Peptide-1 Promotes Human Neuroblastoma Differentiation<br \/>\nvia the PI3K-AKT Axis. Biology (Basel). 2020 Oct 22;9(11):348. doi:<br \/>\n10.3390\/biology9110348. PMID: 33105690; PMCID: PMC7690389.<\/p>\n<p>17: Chen CY, Chao YM, Lin HF, Chen CJ, Chen CS, Yang JL, Chan JYH, Juo SH.<br \/>\nmiR-195 reduces age-related blood-brain barrier leakage caused by<br \/>\nthrombospondin-1-mediated selective autophagy. Aging Cell. 2020<br \/>\nNov;19(11):e13236. doi: 10.1111\/acel.13236. Epub 2020 Oct 7. PMID: 33029941;<br \/>\nPMCID: PMC7681043.<\/p>\n<p>18: Lwin T, Yang JL, Ngampramuan S, Viwatpinyo K, Chancharoen P, Veschsanit N,<br \/>\nPinyomahakul J, Govitrapong P, Mukda S. Melatonin ameliorates methamphetamine-<br \/>\ninduced cognitive impairments by inhibiting neuroinflammation via suppression of<br \/>\nthe TLR4\/MyD88\/NF\u03baB signaling pathway in the mouse hippocampus. Prog<br \/>\nNeuropsychopharmacol Biol Psychiatry. 2021 Dec 20;111:110109. doi:<br \/>\n10.1016\/j.pnpbp.2020.110109. Epub 2020 Sep 15. PMID: 32941923.<\/p>\n<p>19: Chen SD, Pan HY, Huang JB, Liu XP, Li JH, Ho CJ, Tsai MH, Yang JL, Chen SF,<br \/>\nChen NC, Chuang YC. Circulating MicroRNAs from Serum Exosomes May Serve as a<br \/>\nPutative Biomarker in the Diagnosis and Treatment of Patients with Focal<br \/>\nCortical Dysplasia. Cells. 2020 Aug 10;9(8):1867. doi: 10.3390\/cells9081867.<br \/>\nPMID: 32785072; PMCID: PMC7465068.<\/p>\n<p>20: Chen SD, Yang JL, Lin YC, Chao AC, Yang DI. Emerging Roles of Inhibitor of<br \/>\nDifferentiation-1 in Alzheimer&#8217;s Disease: Cell Cycle Reentry and Beyond. Cells.<br \/>\n2020 Jul 21;9(7):1746. doi: 10.3390\/cells9071746. PMID: 32708313; PMCID:<br \/>\nPMC7409121.<\/p>\n<p>21: Chen WY, Li LC, Wu YH, Yang JL, Tzeng HT. Emerging Roles of<br \/>\nInterleukin-33-responsive Kidney Group 2 Innate Lymphoid Cells in Acute Kidney<br \/>\nInjury. Int J Mol Sci. 2020 Feb 24;21(4):1544. doi: 10.3390\/ijms21041544. PMID:<br \/>\n32102434; PMCID: PMC7073188.<\/p>\n<p>22: Yang JL, Yang YR, Chen SD. The potential of drug repurposing combined with<br \/>\nreperfusion therapy in cerebral ischemic stroke: A supplementary strategy to<br \/>\nendovascular thrombectomy. Life Sci. 2019 Nov 1;236:116889. doi:<br \/>\n10.1016\/j.lfs.2019.116889. Epub 2019 Oct 11. PMID: 31610199.<\/p>\n<p>23: Chen SD, Yang JL, Lin TK, Yang DI. Emerging Roles of Sestrins in<br \/>\nNeurodegenerative Diseases: Counteracting Oxidative Stress and Beyond. J Clin<br \/>\nMed. 2019 Jul 9;8(7):1001. doi: 10.3390\/jcm8071001. PMID: 31324048; PMCID:<br \/>\nPMC6678886.<\/p>\n<p>24: Mukda S, Tsai CY, Leu S, Yang JL, Chan SHH. Pinin protects astrocytes from<br \/>\ncell death after acute ischemic stroke via maintenance of mitochondrial anti-<br \/>\napoptotic and bioenergetics functions. J Biomed Sci. 2019 Jun 5;26(1):43. doi:<br \/>\n10.1186\/s12929-019-0538-5. PMID: 31167655; PMCID: PMC6549339.<\/p>\n<p>25: Tsai YH, Yang JL, Lee IN, Yang JT, Lin LC, Huang YC, Yeh MY, Weng HH, Su CH.<br \/>\nEffects of Dehydration on Brain Perfusion and Infarct Core After Acute Middle<br \/>\nCerebral Artery Occlusion in Rats: Evidence From High-Field Magnetic Resonance<br \/>\nImaging. Front Neurol. 2018 Sep 20;9:786. doi: 10.3389\/fneur.2018.00786. PMID:<br \/>\n30294297; PMCID: PMC6158308.<\/p>\n<p>26: Li LC, Yang JL, Lee WC, Chen JB, Lee CT, Wang PW, Vaghese Z, Chen WY.<br \/>\nPalmitate aggravates proteinuria-induced cell death and inflammation via<br \/>\nCD36-inflammasome axis in the proximal tubular cells of obese mice. Am J Physiol<br \/>\nRenal Physiol. 2018 Dec 1;315(6):F1720-F1731. doi: 10.1152\/ajprenal.00536.2017.<br \/>\nEpub 2018 Sep 19. PMID: 30230367.<\/p>\n<p>27: Chen WY, Tsai TH, Yang JL, Li LC. Therapeutic Strategies for Targeting<br \/>\nIL-33\/ST2 Signalling for the Treatment of Inflammatory Diseases. Cell Physiol<br \/>\nBiochem. 2018;49(1):349-358. doi: 10.1159\/000492885. Epub 2018 Aug 23. PMID:<br \/>\n30138941.<\/p>\n<p>28: Chen SD, Yang JL, Hwang WC, Yang DI. Emerging Roles of Sonic Hedgehog in<br \/>\nAdult Neurological Diseases: Neurogenesis and Beyond. Int J Mol Sci. 2018 Aug<br \/>\n16;19(8):2423. doi: 10.3390\/ijms19082423. PMID: 30115884; PMCID: PMC6121355.<\/p>\n<p>29: Chen WY, Yang JL, Wu YH, Li LC, Li RF, Chang YT, Dai LH, Wang WC, Chang YJ.<br \/>\nIL-33\/ST2 axis mediates hyperplasia of intrarenal urothelium in obstructive<br \/>\nrenal injury. Exp Mol Med. 2018 Apr 20;50(4):1-11. doi:<br \/>\n10.1038\/s12276-018-0047-8. PMID: 29674622; PMCID: PMC5938009.<\/p>\n<p>30: Yang JL, Mukda S, Chen SD. Diverse roles of mitochondria in ischemic stroke.<br \/>\nRedox Biol. 2018 Jun;16:263-275. doi: 10.1016\/j.redox.2018.03.002. Epub 2018 Mar<br \/>\n9. PMID: 29549824; PMCID: PMC5854930.<\/p>\n<p>31: Yang JL, Chen WY, Chen SD. The Emerging Role of GLP-1 Receptors in DNA<br \/>\nRepair: Implications in Neurological Disorders. Int J Mol Sci. 2017 Aug<br \/>\n26;18(9):1861. doi: 10.3390\/ijms18091861. PMID: 28846606; PMCID: PMC5618510.<\/p>\n<p>32: Chen WY, Li LC, Yang JL. Emerging Roles of IL-33\/ST2 Axis in Renal Diseases.<br \/>\nInt J Mol Sci. 2017 Apr 7;18(4):783. doi: 10.3390\/ijms18040783. PMID: 28387719;<br \/>\nPMCID: PMC5412367.<\/p>\n<p>33: Yang JL, Chen WY, Chen YP, Kuo CY, Chen SD. Activation of GLP-1 Receptor<br \/>\nEnhances Neuronal Base Excision Repair via PI3K-AKT-Induced Expression of<br \/>\nApurinic\/Apyrimidinic Endonuclease 1. Theranostics. 2016 Sep 2;6(12):2015-2027.<br \/>\ndoi: 10.7150\/thno.15993. PMID: 27698937; PMCID: PMC5039677.<\/p>\n<p>34: Chuang YC, Lin TK, Yang DI, Yang JL, Liou CW, Chen SD. Peroxisome<br \/>\nproliferator-activated receptor-gamma dependent pathway reduces the<br \/>\nphosphorylation of dynamin-related protein 1 and ameliorates hippocampal injury<br \/>\ninduced by global ischemia in rats. J Biomed Sci. 2016 May 12;23(1):44. doi:<br \/>\n10.1186\/s12929-016-0262-3. PMID: 27175924; PMCID: PMC4865999.<\/p>\n<p>35: Chen WY, Chang YJ, Su CH, Tsai TH, Chen SD, Hsing CH, Yang JL. Upregulation<br \/>\nof Interleukin-33 in obstructive renal injury. Biochem Biophys Res Commun. 2016<br \/>\nMay 13;473(4):1026-1032. doi: 10.1016\/j.bbrc.2016.04.010. Epub 2016 Apr 8. PMID:<br \/>\n27067050.<\/p>\n<p>36: Hsieh MC, Tsai CY, Liao MC, Yang JL, Su CH, Chen JH. Quantitative<br \/>\nSusceptibility Mapping-Based Microscopy of Magnetic Resonance Venography (QSM-<br \/>\nmMRV) for In Vivo Morphologically and Functionally Assessing<br \/>\nCerebromicrovasculature in Rat Stroke Model. PLoS One. 2016 Mar<br \/>\n14;11(3):e0149602. doi: 10.1371\/journal.pone.0149602. PMID: 26974842; PMCID:<br \/>\nPMC4790912.<\/p>\n<p>37: Chuang YC, Yang JL, Yang DI, Lin TK, Liou CW, Chen SD. Roles of Sestrin2 and<br \/>\nRibosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal<br \/>\nInjury. Int J Mol Sci. 2015 Nov 4;16(11):26406-16. doi: 10.3390\/ijms161125963.<br \/>\nPMID: 26556340; PMCID: PMC4661822.<\/p>\n<p>38: Tsai TH, Sun CK, Su CH, Sung PH, Chua S, Zhen YY, Leu S, Chang HW, Yang JL,<br \/>\nYip HK. Sitagliptin attenuated brain damage and cognitive impairment in mice<br \/>\nwith chronic cerebral hypo-perfusion through suppressing oxidative stress and<br \/>\ninflammatory reaction. J Hypertens. 2015 May;33(5):1001-13. doi:<br \/>\n10.1097\/HJH.0000000000000529. PMID: 25689400.<\/p>\n<p>39: Fan CQ, Leu S, Sheu JJ, Zhen YY, Tsai TH, Chen YL, Chung SY, Chai HT, Sun<br \/>\nCK, Yang JL, Chang HW, Ko SF, Yip HK. Prompt bone marrow-derived mesenchymal<br \/>\nstem cell therapy enables early porcine heart function recovery from acute<br \/>\nmyocardial infarction. Int Heart J. 2014;55(4):362-71. doi: 10.1536\/ihj.14-007.<br \/>\nEpub 2014 Jun 25. PMID: 24965596.<\/p>\n<p>40: Yang JL, Lin YT, Chuang PC, Bohr VA, Mattson MP. BDNF and exercise enhance<br \/>\nneuronal DNA repair by stimulating CREB-mediated production of<br \/>\napurinic\/apyrimidinic endonuclease 1. Neuromolecular Med. 2014<br \/>\nMar;16(1):161-174. doi: 10.1007\/s12017-013-8270-x. Epub 2013 Oct 10. PMID:<br \/>\n24114393; PMCID: PMC3948322.<\/p>\n<p>41: Chen YT, Yang CC, Zhen YY, Wallace CG, Yang JL, Sun CK, Tsai TH, Sheu JJ,<br \/>\nChua S, Chang CL, Cho CL, Leu S, Yip HK. Cyclosporine-assisted adipose-derived<br \/>\nmesenchymal stem cell therapy to mitigate acute kidney ischemia-reperfusion<br \/>\ninjury. Stem Cell Res Ther. 2013 May 31;4(3):62. doi: 10.1186\/scrt212. PMID:<br \/>\n23726287; PMCID: PMC3706768.<\/p>\n<p>42: Sykora P, Yang JL, Ferrarelli LK, Tian J, Tadokoro T, Kulkarni A, Weissman<br \/>\nL, Keijzers G, Wilson DM 3rd, Mattson MP, Bohr VA. Modulation of DNA base<br \/>\nexcision repair during neuronal differentiation. Neurobiol Aging. 2013<br \/>\nJul;34(7):1717-27. doi: 10.1016\/j.neurobiolaging.2012.12.016. Epub 2013 Feb 1.<br \/>\nPMID: 23375654; PMCID: PMC5576894.<\/p>\n<p>43: Cheng A, Wan R, Yang JL, Kamimura N, Son TG, Ouyang X, Luo Y, Okun E,<br \/>\nMattson MP. Involvement of PGC-1\u03b1 in the formation and maintenance of neuronal<br \/>\ndendritic spines. Nat Commun. 2012;3:1250. doi: 10.1038\/ncomms2238. PMID:<br \/>\n23212379; PMCID: PMC4091730.<\/p>\n<p>44: Sheu JJ, Lin KC, Tsai CY, Tsai TH, Leu S, Yen CH, Chen YL, Chang HW, Sun CK,<br \/>\nChua S, Yang JL, Yip HK. Combination of cilostazol and clopidogrel attenuates<br \/>\nrat critical limb ischemia. J Transl Med. 2012 Aug 16;10:164. doi:<br \/>\n10.1186\/1479-5876-10-164. PMID: 22897925; PMCID: PMC3479044.<\/p>\n<p>45: Yang JL, Sykora P, Wilson DM 3rd, Mattson MP, Bohr VA. The excitatory<br \/>\nneurotransmitter glutamate stimulates DNA repair to increase neuronal<br \/>\nresiliency. Mech Ageing Dev. 2011 Aug;132(8-9):405-11. doi:<br \/>\n10.1016\/j.mad.2011.06.005. Epub 2011 Jun 25. PMID: 21729715; PMCID: PMC3367503.<\/p>\n<p>46: Gredilla R, Weissman L, Yang JL, Bohr VA, Stevnsner T. Mitochondrial base<br \/>\nexcision repair in mouse synaptosomes during normal aging and in a model of<br \/>\nAlzheimer&#8217;s disease. Neurobiol Aging. 2012 Apr;33(4):694-707. doi:<br \/>\n10.1016\/j.neurobiolaging.2010.06.019. Epub 2010 Aug 14. PMID: 20708822; PMCID:<br \/>\nPMC3041866.<\/p>\n<p>47: Yang JL, Tadokoro T, Keijzers G, Mattson MP, Bohr VA. Neurons efficiently<br \/>\nrepair glutamate-induced oxidative DNA damage by a process involving CREB-<br \/>\nmediated up-regulation of apurinic endonuclease 1. J Biol Chem. 2010 Sep<br \/>\n3;285(36):28191-9. doi: 10.1074\/jbc.M109.082883. Epub 2010 Jun 23. PMID:<br \/>\n20573957; PMCID: PMC2934684.<\/p>\n<p>48: Yang JL, Weissman L, Bohr VA, Mattson MP. Mitochondrial DNA damage and<br \/>\nrepair in neurodegenerative disorders. DNA Repair (Amst). 2008 Jul<br \/>\n1;7(7):1110-20. doi: 10.1016\/j.dnarep.2008.03.012. Epub 2008 May 7. PMID:<br \/>\n18463003; PMCID: PMC2442166.<\/p>\n\n        <\/div>\n    <\/div>\n<\/section>\n\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div aria-controls=\"tab-id-3\" role=\"tab\" tabindex=\"0\" data-fake-id=\"#tab-id-3\" class=\"tab \"  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue80b' data-av_iconfont='entypo-fontello'><\/span>\u7814\u7a76\u5718\u968a<\/div>\n    <div id=\"tab-id-3-container\" class=\"tab_content \" aria-hidden=\"true\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<h4 style=\"text-align: left;\"><\/h4>\n<table width=\"720\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td bgcolor=\"#FFFFFF\">\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-3728 size-full\" src=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2022\/02\/LeeSY_270.jpg\" alt=\"\" width=\"180\" height=\"270\" \/><\/p>\n<h4 style=\"text-align: center;\"><strong>\u674e\u59dd\u7469<\/strong><\/h4>\n<h5 style=\"text-align: center;\">\u7814\u7a76\u52a9\u7406<br \/>\nResearch Assistant<\/h5>\n<\/td>\n<td bgcolor=\"#FFFFFF\">\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-3928 size-full\" src=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2023\/05\/HYLu_270.jpg\" alt=\"\" width=\"180\" height=\"270\" \/><\/p>\n<h4 style=\"text-align: center;\"><strong>\u76e7\u5ba3\u807f<\/strong><\/h4>\n<h5 style=\"text-align: center;\">\u7814\u7a76\u52a9\u7406<br \/>\nResearch Assistant<\/h5>\n<\/td>\n<td bgcolor=\"#FFFFFF\">\n<h4 style=\"text-align: center;\"><\/h4>\n<h5 style=\"text-align: center;\"><\/h5>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n        <\/div>\n    <\/div>\n<\/section>\n\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div aria-controls=\"tab-id-4\" role=\"tab\" tabindex=\"0\" data-fake-id=\"#tab-id-4\" class=\"tab \"  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue840' data-av_iconfont='entypo-fontello'><\/span>\u5b78\u8853\u5c65\u6b77<\/div>\n    <div id=\"tab-id-4-container\" class=\"tab_content \" aria-hidden=\"true\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<p><strong>EDUCATION: <\/strong><\/p>\n<p>1999 &#8211; 2006 Ph.D.<\/p>\n<p>Department of Biology, Neuroscience Program,<\/p>\n<p>University of Texas at San Antonio, San Antonio, Texas USA<\/p>\n<p><strong>PROFESSIONAL EXPERIENCE: <\/strong><\/p>\n<p>2021\/8 ~ present\u00a0\u00a0\u00a0 <strong>Professor<\/strong><\/p>\n<p>2018\/8 ~ 2021\/7\u00a0\u00a0\u00a0 <strong>Associate Professor<\/strong><\/p>\n<p>2011\/8 ~ 2018\/7 \u00a0\u00a0 <strong>Assistant Professor <\/strong><\/p>\n<p>Institute for Translational Research in Biomedicine,<\/p>\n<p>Kaohsiung Chang Gung Memorial Hospital,<\/p>\n<p>Kaohsiung, Taiwan<\/p>\n<p>2007\/1 ~ 2011\/7\u00a0\u00a0\u00a0 <strong>Postdoctoral Research Fellow <\/strong><\/p>\n<p>Laboratory of Molecular Gerontology and Laboratory of Neurosciences,<\/p>\n<p>National Institute on Aging, National Institute of Health, Baltimore, Maryland USA<\/p>\n<p>2006\/1 ~ 2006\/11\u00a0\u00a0 <strong>Research Scientist Associate <\/strong><\/p>\n<p>Department of Biology<\/p>\n<p>University of Texas at San Antonio, San Antonio, Texas USA<\/p>\n<p>2002\/9 ~ 2005\/12\u00a0\u00a0\u00a0 <strong>Instructor of Cellular Biology Laboratory <\/strong><\/p>\n<p>Department of Biology<\/p>\n<p>University of Texas at San Antonio, San Antonio, Texas USA<\/p>\n<p>2001\/9 ~ 2001\/12\u00a0\u00a0\u00a0 <strong>Instructor of Molecular Biology Laboratory<\/strong><\/p>\n<p>Department of Biology<\/p>\n<p>University of Texas at San Antonio, San Antonio, Texas USA<\/p>\n<p>2000\/9 ~ 2002\/5\u00a0\u00a0\u00a0\u00a0 <strong>Instructor of Laboratory Investigations in Biology<\/strong><\/p>\n<p>Department of Biology<\/p>\n<p>University of Texas at San Antonio, San Antonio, Texas USA<\/p>\n<p>1997\/1 ~ 1999\/8\u00a0\u00a0\u00a0 <strong>Graduate Research Assistant<\/strong><\/p>\n<p>Department of Biology<\/p>\n<p>University of Texas at San Antonio, San Antonio, Texas USA<\/p>\n<p><strong>AWARDS AND RESEARCH SUPPORT: <\/strong><\/p>\n<p>2009\u00a0 Fellow Achievement Research Excellence Award, National Institute of Health<\/p>\n<p>2001 \u00a0Graduate Travel Award<\/p>\n<p>1998 \u00a0\u00a0University Graduate Small Grant<\/p>\n<p>1997 \u00a0\u00a0University Graduate Small Grant<\/p>\n<p><strong>RESEARCH INTERESTS: <\/strong><\/p>\n<p>1. DNA Damage and Repair in Neurons and Astrocytes<\/p>\n<p>2. Roles of GLP-1 in Neurons and Glial Cells<\/p>\n<p>3. Diagnosis and Therapy on Alzheimer\u2019s Disease and Ischemic Stroke<\/p>\n\n        <\/div>\n    <\/div>\n<\/section>\n\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":443,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages\/1988"}],"collection":[{"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/comments?post=1988"}],"version-history":[{"count":31,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages\/1988\/revisions"}],"predecessor-version":[{"id":4645,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages\/1988\/revisions\/4645"}],"up":[{"embeddable":true,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages\/443"}],"wp:attachment":[{"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/media?parent=1988"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}