{"id":1666,"date":"2019-06-04T23:43:04","date_gmt":"2019-06-04T15:43:04","guid":{"rendered":"https:\/\/itrbm.org\/tw\/?page_id=1666"},"modified":"2026-08-28T09:35:32","modified_gmt":"2026-08-28T01:35:32","slug":"huang-kt","status":"publish","type":"page","link":"https:\/\/itrbm.org\/tw\/members\/huang-kt\/","title":{"rendered":"\u9ec3\u5ee3\u6148 \u526f\u6559\u6388"},"content":{"rendered":"<div id='av_section_1' class='avia-section main_color avia-section-large avia-no-border-styling avia-full-stretch av-section-color-overlay-active avia-bg-style-scroll  avia-builder-el-0  el_before_av_one_fourth  avia-builder-el-first   container_wrap sidebar_left' style='background-repeat: no-repeat; background-image: url(https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/03\/dna-1.jpg);background-attachment: scroll; background-position: center center;  '  data-section-bg-repeat='stretch'><div class='av-section-color-overlay-wrap'><div class='av-section-color-overlay' style='opacity: 0.2; background-color: #000000; '><\/div><div class='container' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-small units'><div class='post-entry post-entry-type-page post-entry-1666'><div class='entry-content-wrapper clearfix'>\n<div style='padding-bottom:10px; color:#ffffff;font-size:44px;' class='av-special-heading av-special-heading-h1 custom-color-heading blockquote modern-quote modern-centered  avia-builder-el-1  avia-builder-el-no-sibling  av-inherit-size '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >\u6210\u54e1\u4ecb\u7d39<\/h1><div class='special-heading-border'><div class='special-heading-inner-border' style='border-color:#ffffff'><\/div><\/div><\/div>\n<\/div><\/div><\/main><!-- close content main element --><\/div><\/div><\/div><div id='after_section_1' class='main_color av_default_container_wrap container_wrap sidebar_left' style=' '  ><div class='container' ><div class='template-page content  av-content-small units'><div class='post-entry post-entry-type-page post-entry-1666'><div class='entry-content-wrapper clearfix'>\n<div class=\"flex_column av_one_fourth  flex_column_div av-zero-column-padding first  avia-builder-el-2  el_after_av_section  el_before_av_one_fourth  avia-builder-el-first  \" style='border-radius:0px; '><div class='avia-image-container  av-styling-    avia-builder-el-3  avia-builder-el-no-sibling  avia-align-left '  itemprop=\"ImageObject\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  ><div class='avia-image-container-inner'><div class='avia-image-overlay-wrap'><img class='avia_image' src='https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2025\/05\/9B2A2512-HuangKT_240.jpg' alt='' title='9B2A2512 HuangKT 240' height=\"240\" width=\"180\"  itemprop=\"thumbnailUrl\"  \/><\/div><\/div><\/div><\/div>\n<div class=\"flex_column av_one_fourth  flex_column_div av-zero-column-padding   avia-builder-el-4  el_after_av_one_fourth  el_before_av_one_half  \" style='border-radius:0px; '><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock  '   itemprop=\"text\" ><h3><strong><span style=\"font-size: 20px; color: #109bc5;\">\u9ec3\u5ee3\u6148<\/span><\/strong><br \/>\n<span style=\"font-size: 16px; color: #333333;\">\u526f\u6559\u6388<\/span><\/h3>\n<h5><span style=\"color: #333333;\">\u6162\u6027\u809d\u75c5\u8207\u809d\u764c<\/span><br \/>\n<span style=\"color: #333333;\">\u8102\u8cea\u4ee3\u8b1d\u8207\u8102\u80aa\u7d30\u80de\u5206\u5316<\/span><br \/>\n<span style=\"color: #333333;\">\u4fe1\u606f\u50b3\u905e\u8207\u57fa\u56e0\u8abf\u63a7<\/span><\/h5>\n<\/div><\/section><\/div>\n<div class=\"flex_column av_one_half  flex_column_div av-zero-column-padding   avia-builder-el-6  el_after_av_one_fourth  el_before_av_hr  \" style='border-radius:0px; '><div class='avia-icon-list-container   avia-builder-el-7  avia-builder-el-no-sibling '><ul class='avia-icon-list avia-icon-list-left av-iconlist-small avia_animate_when_almost_visible avia-iconlist-animate'>\n<li><div  style='font-size:14px; ' class='iconlist_icon  avia-font-entypo-fontello'><span class='iconlist-char ' aria-hidden='true' data-av_icon='\ue854' data-av_iconfont='entypo-fontello'><\/span><\/div><article class=\"article-icon-entry \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='iconlist_content_wrap'><header class=\"entry-content-header\"><div class='av_iconlist_title iconlist_title_small  '  itemprop=\"headline\"   style='font-size:14px; '>\u806f\u7d61\u96fb\u8a71<\/div><\/header><div class='iconlist_content  '  itemprop=\"text\"  ><h5>(07) 731-7123 ext 8193<\/h5>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><div class='iconlist-timeline'><\/div><\/li>\n<li><div  style='font-size:14px; ' class='iconlist_icon  avia-font-entypo-fontello'><span class='iconlist-char ' aria-hidden='true' data-av_icon='\ue805' data-av_iconfont='entypo-fontello'><\/span><\/div><article class=\"article-icon-entry \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='iconlist_content_wrap'><header class=\"entry-content-header\"><div class='av_iconlist_title iconlist_title_small  '  itemprop=\"headline\"   style='font-size:14px; '>\u96fb\u5b50\u90f5\u4ef6\u4fe1\u7bb1<\/div><\/header><div class='iconlist_content  '  itemprop=\"text\"  ><h5>huangkt@cgmh.org.tw<\/h5>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><div class='iconlist-timeline'><\/div><\/li>\n<\/ul><\/div><\/div>\n<div style='height:20px' class='hr hr-invisible   avia-builder-el-8  el_after_av_one_half  el_before_av_tab_container '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div>\n<div class=\"tabcontainer   top_tab   avia-builder-el-9  el_after_av_hr  avia-builder-el-last \">\n\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div aria-controls=\"tab-id-1\" role=\"tab\" tabindex=\"0\" data-fake-id=\"#tab-id-1\" class=\"tab active_tab\"  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue864' data-av_iconfont='entypo-fontello'><\/span>\u7814\u7a76\u7c21\u4ecb<\/div>\n    <div id=\"tab-id-1-container\" class=\"tab_content active_tab_content\" aria-hidden=\"false\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<h4><strong>\u8272\u7d20\u4e0a\u76ae\u884d\u751f\u56e0\u5b50 (PEDF) \u5728\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u708e\u7684\u529f\u80fd\u6027\u7814\u7a76<\/strong><\/h4>\n<p>\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d (NAFLD) \u662f\u6162\u6027\u809d\u75c5\u7684\u4e3b\u8981\u6210\u56e0\uff0c\u5f71\u97ff\u5168\u4e16\u754c\u7d04\u4e09\u5206\u4e4b\u4e00\u7684\u4eba\u53e3\uff0c\u4e5f\u5e38\u88ab\u8996\u70ba\u4ee3\u8b1d\u75c7\u5019\u7fa4\u5728\u809d\u81df\u7684\u5177\u9ad4\u8868\u5fb5\u3002\u80a5\u80d6\u8207\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u7684\u666e\u904d\u7a0b\u5ea6\u548c\u56b4\u91cd\u6027\u6709\u9ad8\u5ea6\u76f8\u95dc\u6027\u3002\u975e\u9152\u7cbe\u8102\u80aa\u809d\u96a8\u75be\u75c5\u9032\u7a0b\u5340\u5206\u70ba\u55ae\u7d14\u8102\u80aa\u8b8a\u6027\u548c\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u708e (NASH)\uff0c\u5f8c\u8005\u6709\u6f14\u8b8a\u6210\u809d\u7e96\u7dad\u5316\u3001\u751a\u81f3\u809d\u786c\u5316\u7684\u5371\u96aa\u3002\u96d6\u7136\u55ae\u7d14\u8102\u80aa\u8b8a\u6027\u70ba\u4e09\u9178\u7518\u6cb9\u916f\u7684\u7d2f\u7a4d\u4e14\u5927\u591a\u4e0d\u5f71\u97ff\u6b63\u5e38\u809d\u529f\u80fd\uff0c\u5177\u6bd2\u6027\u7684\u8102\u8cea\u4ee3\u8b1d\u7269\u6703\u96a8\u75be\u75c5\u9032\u7a0b\u9010\u6f38\u589e\u52a0\u4e26\u5f15\u767c\u6c27\u5316\u58d3\u529b\u548c\u6162\u6027\u767c\u708e\uff0c\u9032\u4e00\u6b65\u9020\u6210\u80f0\u5cf6\u7d20\u6297\u6027\u548c\u904e\u5ea6\u7684\u8102\u80aa\u6c34\u89e3\uff0c\u6700\u7d42\u5c0e\u81f4\u75be\u75c5\u60e1\u5316\u3002\u7531\u65bc NASH \u76ee\u524d\u7121\u6709\u6548\u7642\u6cd5\uff0c\u7814\u7a76\u81f4\u75c5\u7684\u5206\u5b50\u6a5f\u5236\u6709\u52a9\u65bc\u767c\u73fe\u9810\u9632\u548c\u6cbb\u7642\u7684\u65b0\u6a19\u7684\u3002<\/p>\n<p style=\"text-align: left;\">\u672c<a href=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangNASH_1024.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-1688\" src=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangNASH_1024-300x194.png\" alt=\"\" width=\"350\" height=\"226\" srcset=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangNASH_1024-300x194.png 300w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangNASH_1024-768x497.png 768w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangNASH_1024-705x456.png 705w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangNASH_1024-450x291.png 450w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangNASH_1024.png 1024w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/><\/a>\u7814\u7a76\u5ba4\u76ee\u524d\u4e3b\u8981\u805a\u7126\u5728\u8272\u7d20\u4e0a\u76ae\u884d\u751f\u56e0\u5b50 (PEDF) \u9019\u500b\u591a\u529f\u80fd\u86cb\u767d\u8cea\uff0c\u5176\u4e2d\u6700\u70ba\u4eba\u719f\u77e5\u7684\u662f\u4fc3\u9032\u795e\u7d93\u7d30\u80de\u5206\u5316\u548c\u6291\u5236\u8840\u7ba1\u65b0\u751f\u3002PEDF \u5728\u8102\u8cea\u4ee3\u8b1d\u89d2\u8272\u7684\u5efa\u7acb\u662f\u56e0\u767c\u73fe\u5b83\u5177\u6709\u8f14\u52a9\u8102\u80aa\u4e09\u9178\u7518\u6cb9\u916f\u6c34\u89e3\u9176 (ATGL) \u7684\u4f5c\u7528\u3002\u6211\u5011\u8fd1\u4f86\u7684\u7814\u7a76\u767c\u73fe\uff0cPEDF \u6703\u900f\u904e ATGL \u8abf\u7bc0\u8102\u80aa\u9178\u8f49\u4f4d\u9176 (CD36) \u7684\u8868\u73fe\uff0c\u9032\u800c\u6291\u5236\u8102\u80aa\u7d30\u80de\u5206\u5316\u3002\u7531\u65bc CD36 \u662f\u7d30\u80de\u651d\u53d6\u8102\u80aa\u9178\u7684\u91cd\u8981\u9175\u7d20\uff0c\u6211\u5011\u5047\u8a2d PEDF \u4e5f\u6703\u900f\u904e ATGL-CD36 \u7684\u8def\u5f91\u5f15\u97ff\u809d\u81df\u8102\u8cea\u7d2f\u7a4d\u53ca\u5176\u76f8\u95dc\u529f\u80fd\u3002\u6211\u5011\u4e5f\u5f9e NASH \u7684\u5c0f\u9f20\u6a21\u5f0f\u4e2d\u9a57\u8b49 PEDF\u3001ATGL\u3001CD36 \u5728\u75be\u75c5\u9032\u7a0b\u7684\u8abf\u7bc0\u89d2\u8272\uff0c\u4e26\u9032\u4e00\u6b65\u95e1\u8ff0 PEDF \u8a0a\u606f\u50b3\u905e\u800c\u5f71\u97ff\u4e0b\u6e38\u8207\u81f4\u75c5\u76f8\u95dc\u7684\u6a5f\u5236\uff0c\u5982\u6cb9\u6ef4\u5f62\u6210\u3001\u8102\u80aa\u7d30\u80de\u80a5\u5927\u548c\u514d\u75ab\u53cd\u61c9\u7b49\u3002\u6211\u5011\u4e5f\u85c9\u7531\u6291\u5236 CD36 \u6d3b\u6027\uff0c\u5728\u5c0f\u9f20 NASH \u6a21\u578b\u63a2\u8a0e\u53ef\u80fd\u7684\u6cbb\u7642\u9014\u5f91\u3002<\/p>\n<h4><strong>\u9223\u7db2\u4f34\u8b77\u86cb\u767d (calreticulin) \u5728\u809d\u7e96\u7dad\u5316\u904e\u7a0b\u7684\u591a\u91cd\u89d2\u8272<\/strong><\/h4>\n<p>\u809d\u7e96\u7dad\u5316\u5728\u53f0\u7063\u548c\u5168\u4e16\u754c\u90fd\u662f\u56b4\u91cd\u5f71\u97ff\u5065\u5eb7\u7684\u75be\u75c5\uff0c\u5176\u4e3b\u8981\u7279\u5fb5\u662f\u7d30\u80de\u5916\u57fa\u8cea\u904e\u5ea6\u7d2f\u7a4d\u9020\u6210\u7684\u809d\u529f\u80fd\u7570\u5e38\uff0c\u809d\u786c\u5316\u75c5\u4eba\u4e5f\u662f\u809d\u7d30\u80de\u764c\u7684\u9ad8\u5371\u96aa\u7fa4\u3002\u809d\u7e96\u7dad\u5316\u662f\u6162\u6027\u809d\u640d\u50b7\u4e0d\u65b7\u4fee\u88dc\u7684\u7d50\u679c\uff0c\u640d\u50b7\u7684\u809d\u7d30\u80de\u548c\u6ef2\u5165\u7684\u767c\u708e\u6027\u514d\u75ab\u7d30\u80de\u6703\u88fd\u9020\u4fc3\u9032\u7e96\u7dad\u5316\u7684\u56e0\u5b50\uff0c\u9032\u800c\u6d3b\u5316\u809d\u81df\u661f\u72c0\u7d30\u80de\u3002\u661f\u72c0\u7d30\u80de\u6d3b\u5316\u6703\u5927\u91cf\u589e\u751f\uff0c\u4e26\u4fc3\u9032\u7d30\u80de\u5916\u57fa\u8cea\u7684\u751f\u6210\u3002\u6162\u6027\u809d\u640d\u50b7\u4e5f\u6703\u9020\u6210\u809d\u7d30\u80de\u6b7b\u4ea1\uff0c\u8da8\u4f7f\u4e00\u4e9b\u539f\u672c\u5728\u7d30\u80de\u5167\u7684\u86cb\u767d\u8cea\u66b4\u9732\u51fa\u4f86\uff0c\u9019\u4e9b\u86cb\u767d\u8cea\u5e38\u8868\u73fe\u4e0d\u540c\u65bc\u539f\u672c\u751f\u7406\u529f\u80fd\u7684\u4f5c\u7528\uff0c\u5982\u672c\u7814\u7a76\u5ba4\u6240\u63a2\u8a0e\u7684\uff0c\u539f\u672c\u4f4d\u65bc\u5167\u8cea\u7db2\u4e2d\u5177\u6709\u76e3\u63a7\u86cb\u767d\u8cea\u647a\u758a\u4e26\u8abf\u7bc0\u7d30\u80de\u9223\u96e2\u5b50\u6046\u5b9a\u529f\u80fd\u7684\u9223\u7db2\u4f34\u8b77\u86cb\u767d (calreticulin)\u3002<\/p>\n<p><a href=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangCRT1024.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-1690\" src=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangCRT1024-300x156.png\" alt=\"\" width=\"350\" height=\"183\" srcset=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangCRT1024-300x156.png 300w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangCRT1024-768x401.png 768w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangCRT1024-705x368.png 705w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangCRT1024-450x235.png 450w, https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/HuangCRT1024.png 1024w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/><\/a>\u8fd1\u4f86\u7684\u6587\u737b\u6307\u51fa\u66b4\u9732\u65bc\u7d30\u80de\u5916\u7684\u9223\u7db2\u4f34\u8b77\u86cb\u767d\u5177\u6709\u8abf\u7bc0\u5148\u5929\u6027\u514d\u75ab\u53cd\u61c9\u7684\u4f5c\u7528\u3002\u6211\u5011\u5be6\u9a57\u6578\u64da\u986f\u793a\uff0c\u809d\u7e96\u7dad\u5316\u5c0f\u9f20\u7684\u9223\u7db2\u4f34\u8b77\u86cb\u767d\u8868\u73fe\u91cf\u589e\u52a0\uff0c\u89c0\u5bdf\u809d\u7d44\u7e54\u5207\u7247\u7684\u514d\u75ab\u67d3\u8272\u5247\u767c\u73fe\uff0c\u8868\u73fe\u91cf\u589e\u52a0\u96c6\u4e2d\u65bc\u809d\u7ac7\u72c0\u9699\u53ca\u5176\u5468\u570d\u53d7\u5230\u640d\u50b7\u7684\u809d\u7d44\u7e54\uff0c\u4e14\u6709\u5448\u73fe\u65bc\u7d30\u80de\u8868\u9762\u7684\u73fe\u8c61\u3002\u6709\u8da3\u7684\u662f\uff0c\u5728\u7d30\u80de\u5be6\u9a57\u4e2d\uff0c\u5916\u52a0\u7684\u9223\u7db2\u4f34\u8b77\u86cb\u767d\u96d6\u5177\u6709\u8a98\u5c0e\u4fc3\u9032\u767c\u708e\u7d30\u80de\u6fc0\u7d20\u751f\u6210\u7684\u4f5c\u7528\uff0c\u4f46\u540c\u6642\u6703\u6e1b\u5c11\u661f\u72c0\u7d30\u80de\u6d3b\u5316\u6a19\u8a18\u7684\u8868\u73fe\uff0c\u4e26\u6291\u5236\u661f\u72c0\u7d30\u80de\u589e\u751f\u3002\u6211\u5011\u56e0\u6b64\u5047\u8a2d\u5167\u8cea\u7db2\u548c\u7d30\u80de\u5916\u7684\u9223\u7db2\u4f34\u8b77\u86cb\u767d\u5747\u53c3\u8207\u809d\u7e96\u7dad\u5316\u7684\u904e\u7a0b\uff0c\u4f46\u626e\u6f14\u8457\u4e0d\u540c\u89d2\u8272\u3002\u56e0\u6b64\u6211\u5011\u9032\u4e00\u6b65\u63a2\u8a0e\u9223\u7db2\u4f34\u8b77\u86cb\u767d\u5728\u809d\u7e96\u7dad\u5316\u904e\u7a0b\u7684\u529f\u80fd\uff0c\u4e26\u8a55\u4f30\u7d30\u80de\u5916\u9223\u7db2\u4f34\u8b77\u86cb\u767d\u5728\u809d\u7e96\u7dad\u5316\u5c0f\u9f20\u6a21\u5f0f\u4e2d\u7684\u751f\u7406\u6548\u61c9\u3002<\/p>\n\n        <\/div>\n    <\/div>\n<\/section>\n\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div aria-controls=\"tab-id-2\" role=\"tab\" tabindex=\"0\" data-fake-id=\"#tab-id-2\" class=\"tab \"  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue836' data-av_iconfont='entypo-fontello'><\/span>\u5b78\u8853\u8457\u4f5c<\/div>\n    <div id=\"tab-id-2-container\" class=\"tab_content \" aria-hidden=\"true\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<p><strong>Selected recent publications (<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Huang%2C+Kuang-Tzu\" target=\"_blank\" rel=\"noopener\">Pubmed Search<\/a>)<br \/>\n<\/strong> (\u2020 Contributed equally to the article; * Correspondence author of the article)<\/p>\n<p>Chen CC, Hsu LW, Chen KD, Chiu KW, Kung CP, Li SR, Goto S, Chen CL, <strong>Huang KT*<\/strong>. <em>Extracellular calreticulin regulates fibrogenic and immunogenic properties of hepatic stellate cells.<\/em> International Immunopharmacology, 148:114129 (2025)<\/p>\n<p>Chen CC, Hsu LW, Chen KD, Chiu KW, Kung CP, Li SR, Chen CL, <strong>Huang KT*<\/strong>. <em>Calreticulin regulates hepatic stellate cell activation through modulating TGF-beta-induced Smad signaling.<\/em> Cell Calcium, 121:102895 (2024)<\/p>\n<p><strong>Huang KT<\/strong>, Lin JH, Chang TX, Lin YL, Lee SJ, Zheng YY, Hsueh YH*. <em>Incorporation of high molecular weight gamma-polyglutamic acid in maltodextrin-microencapsulated Bifidobacterium bifidum enhances resistance to simulated gastrointestinal fluids.<\/em> Process Biochemistry, 133:285-291 (2023)<\/p>\n<p>Chen CC, Nakano T, Hsu LW, Chu CY, <strong>Huang KT*<\/strong>. <em>Early Lipid Metabolic Effects of the Anti-Psychotic Drug Olanzapine on Weight Gain and the Associated Gene Expression.<\/em> Neuropsychiatric Disease and Treatment, 18:645-657 (2022)<\/p>\n<p>Chen CC, Hsu LW, Chen KD, Chiu KW, Chen CL, <strong>Huang KT*<\/strong>. <em>Emerging Roles of Calcium Signaling in the Development of Non-Alcoholic Fatty Liver Disease.<\/em> International Journal of Molecular Sciences, 23(1):256 (2022)<\/p>\n<p><strong>Huang KT*<\/strong>, Chen KD, Hsu LW, Kung CP, Li SR, Chen CC, Chiu KW, Goto S, Chen CL. <em>Decreased PEDF Promotes Hepatic Fatty Acid Uptake and Lipid Droplet Formation in the Pathogenesis of NAFLD.<\/em> Nutrients, 12(1):270 (2020)<\/p>\n<p><strong>Huang KT*<\/strong>, Hsu LW, Chen KD, Kung CP, Goto S, Chen CL. <em>Decreased PEDF Expression Promotes Adipogenic Differentiation through the Up-Regulation of CD36.<\/em> International Journal of Molecular Sciences, 19(12):E3992 (2018)<\/p>\n<p><strong>Huang KT*<\/strong>, Lin CC, Tsai MC, Chen KD, Chiu KW. <em>Pigment Epithelium-Derived Factor in Lipid Metabolic Disorders.<\/em> Biomedical Journal, 41(2):102-108 (2018)<\/p>\n<p>Lin CC, Wu CH, Chen LY, Tsai MC, Elsarawy AM, <strong>Huang KT*<\/strong>. <em>Coagulation factor VII gene polymorphisms are not associated with the occurrence or the survival of hepatocellular carcinoma: a report of 37 cases.<\/em> Cancer Biology &amp; Medicine, 15(3):275-281 (2018)<\/p>\n<p><strong>Huang KT<\/strong>, Kuo IY, Tsai MC, Wu CH, Hsu LW, Chen LY, Kung CP, Cheng YF, Goto S, Chou YW, Chen CL, Lin CC, Chen KD*. <em>Factor VII-Induced MicroRNA-135a Inhibits Autophagy and Is Associated with Poor Prognosis in Hepatocellular Carcinoma.<\/em> Molecular Therapy Nucleic Acids, 9:274-283 (2017)<\/p>\n<p>Daubriac J\u2020, Pandya UM\u2020, <strong>Huang KT\u2020<\/strong> (co-first authors), Pavlides SC, Gama P, Blank SV, Shukla P, Crawford SE, Gold LI*. <em>Hormonal and Growth Regulation of Epithelial and Stromal Cells From the Normal and Malignant Endometrium by Pigment Epithelium-Derived Factor.<\/em> Endocrinology, 158(9):2754-2773 (2017)<\/p>\n\n        <\/div>\n    <\/div>\n<\/section>\n\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div aria-controls=\"tab-id-3\" role=\"tab\" tabindex=\"0\" data-fake-id=\"#tab-id-3\" class=\"tab \"  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue80b' data-av_iconfont='entypo-fontello'><\/span>\u7814\u7a76\u5718\u968a<\/div>\n    <div id=\"tab-id-3-container\" class=\"tab_content \" aria-hidden=\"true\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<h4 style=\"text-align: left;\"><strong>\u00a0<\/strong><\/h4>\n<table width=\"240\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td bgcolor=\"#FFFFFF\">\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1694 size-full\" src=\"https:\/\/itrbm.org\/tw\/wp-content\/uploads\/2019\/06\/KungCP240.jpg\" alt=\"\" width=\"180\" height=\"240\" \/><\/p>\n<h4 style=\"text-align: center;\"><strong>\u5b54\u662d\u860b<\/strong><\/h4>\n<h5 style=\"text-align: center;\">\u7814\u7a76\u52a9\u7406<br \/>\nResearch Assistant<\/h5>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n        <\/div>\n    <\/div>\n<\/section>\n\n<section class=\"av_tab_section\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" >    <div aria-controls=\"tab-id-4\" role=\"tab\" tabindex=\"0\" data-fake-id=\"#tab-id-4\" class=\"tab \"  itemprop=\"headline\" ><span class='tab_icon' aria-hidden='true' data-av_icon='\ue840' data-av_iconfont='entypo-fontello'><\/span>\u5b78\u8853\u5c65\u6b77<\/div>\n    <div id=\"tab-id-4-container\" class=\"tab_content \" aria-hidden=\"true\">\n        <div class=\"tab_inner_content invers-color\"  itemprop=\"text\" >\n<p><strong>EDUCATION:<\/strong><b><br \/>\n<\/b><\/p>\n<p>2002 &#8211; 2008\u00a0 Doctor of Philosophy<br \/>\nBiomedical Sciences, University of California, Riverside, Riverside, CA, USA<\/p>\n<p>1996 &#8211; 1998 \u00a0Master of Science<br \/>\nBiochemistry, National Yang-Ming University, Taipei, Taiwan<\/p>\n<p>1992 &#8211; 1996 \u00a0Bachelor of Science<br \/>\nChemical Engineering, National Tsing Hua University, Hsinchu, Taiwan<\/p>\n<p><strong>PROFESSIONAL EXPERIENCE:<\/strong><b><br \/>\n<\/b><\/p>\n<p>2020 &#8211; present\u00a0 Associate Research Fellow<br \/>\n2013 &#8211; 2020 \u00a0Assistant Research Fellow<br \/>\nInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan<\/p>\n<p>My current interest is to identify potential molecular targets (proteins, small RNAs) involved in the initiation and progression of lipid metabolic disorders, chronic liver diseases, and hepatocellular carcinoma.<\/p>\n<p>2009 &#8211; 2013 \u00a0Postdoctoral Fellow<br \/>\nDepartment of Medicine, New York University Medical Center, New York, NY, USA<\/p>\n<p>The research project was focused on hormonal regulation of the cell cycle inhibitor p27\/kip1 in ubiquitin-proteasome degradation system in endometrial carcinoma. I also participated in designing and testing small molecule inhibitors of an E3 ligase (Skp2) that targets p27 for degradation. The other project included a growth-inhibitory protein, pigment epithelium-derived factor, whose expression and mechanisms of action in endometrial cancer were studied.<\/p>\n<p>2003 &#8211; 2008 \u00a0Graduate Research Assistant<br \/>\nDivision of Biomedical Sciences, University of California, Riverside, Riverside, CA, USA<\/p>\n<p>The dissertation project was to investigate the role of a group of naturally occurring, constitutively active prolactin receptors in human prostate and breast cancers. I also actively participated in three additional projects: 1) characterizing a secreted prolactin receptor isoform which counteracts prolactin action, 2) localizing prolactin receptor isoforms in mouse mammary ducts, and 3) searching for potential prolactin binding factors in human milk.<\/p>\n<p><strong>ACADEMIC APPOINTMENT:<\/strong><\/p>\n<p>2014 &#8211; 2015\u00a0 Adjunct Assistant Professor<br \/>\nBachelor Program of Medical Engineering, Cheng Shiu University, Kaohsiung, Taiwan<br \/>\nLecturer in 1) Biochemistry, 2) Introduction to Biotechnology, 3) Bio-electro-mechanical Industry Analysis<\/p>\n<p>2010 &#8211; 2013\u00a0 Teaching Assistant<br \/>\nSackler Institute of Graduate Biomedical Sciences, New York University, New York, NY, USA<br \/>\nLeader in discussion sessions: Foundations of Cell and Molecular Biology II (TGF-\u03b2 Signaling)<\/p>\n<p>2006 &#8211; 2007\u00a0 Teaching Assistant<br \/>\nDepartment of Biology, University of California, Riverside, Riverside, CA, USA<br \/>\nLaboratory sessions; discussion sessions; office hours; grading of laboratory notebooks and exams: Biology 5B (Introduction to Organismal Biology)<\/p>\n<p><strong>PROFESSIONAL ACTIVITIES:<\/strong><\/p>\n<p>2017 &#8211; present\u00a0 Committee member, Basic Science Committee, International Liver Transplantation Society<br \/>\n2006 &#8211; 2013\u00a0 Associate member, Endocrine Society<\/p>\n<p><strong>AWARDS AND HONORS:<\/strong><\/p>\n<p>2018\u00a0 Session moderator\/Oral speaker, The 2018 Joint International Congress of ILTS, ELITA &amp; LICAGE, Lisbon, Portugal.<br \/>\n2016\u00a0 Oral speaker, International Liver Transplantation Society 22nd Annual International Congress, Seoul, Korea<br \/>\n2015\u00a0 Oral speaker, International Liver Transplantation Society 21st Annual International Congress, Chicago, IL, USA<br \/>\n2006 &#8211; 2009 \u00a0Breast Cancer Research Program Predoctoral Traineeship Award<br \/>\nAwarded by the Department of Defense (USA) for three-year predoctoral research titled \u201cThe Role of Constitutively Active Prolactin Receptors in the Natural History of Breast Cancer\u201d.<br \/>\n2007 \u00a0Award for Outstanding Student Research Presentation, Division of Biomedical Sciences, University of California, Riverside<br \/>\n2005 \u00a0Joy K Tilton Cancer Research Award, Division of Biomedical Sciences, University of California, Riverside<br \/>\n2004\u00a0 Cancer Federation Award, Division of Biomedical Sciences, University of California, Riverside. (Featured in <i>Press-Enterprise<\/i>)<br \/>\n2002 &#8211; 2003 \u00a0Dean\u2019s Fellowship, Division of Biomedical Sciences, University of California, Riverside<\/p>\n<p><strong>RESEARCH INTERESTS:<\/strong><b><br \/>\n<\/b><br \/>\n1. Molecular pathogenesis of chronic liver diseases, including cirrhosis, steatohepatitis and hepatocellular carcinoma<br \/>\n2. Molecular mechanisms of adipogenic\/osteogenic differentiation<br \/>\n3. Functional characterization of immunogenic danger signals in the liver<\/p>\n\n        <\/div>\n    <\/div>\n<\/section>\n\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":443,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages\/1666"}],"collection":[{"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/comments?post=1666"}],"version-history":[{"count":16,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages\/1666\/revisions"}],"predecessor-version":[{"id":4885,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages\/1666\/revisions\/4885"}],"up":[{"embeddable":true,"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/pages\/443"}],"wp:attachment":[{"href":"https:\/\/itrbm.org\/tw\/wp-json\/wp\/v2\/media?parent=1666"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}