• Institute for Translational Research in Biomedicine

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About ITRBM

Translational research in biomedicine transcends the boundaries between bench and bedside research. It is the synthesis of ideas, technologies and research outcomes that are associated with a particular health theme.
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Our Members

The governing philosophy of the ITRBM is that clinical and laboratory scientists must work together with an ultimate objective to tackle health-oriented problems.
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Contact Us

Address:
11th Floor, Children’s Building; No.123 Da-Pi Road, Niaosong District, Kaohsiung City, Taiwan
Phone:
+886-7-731-7123 #8099/#8599
E-mail:
contact.itrbm@gmail.com
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Research Highlights

Julie Y.H. Chan, PhD

Lab Anim. 2021 Jan; 50(1): 26-31.
Disproportional cardiovascular depressive effects of isoflurane: Serendipitous findings from a comprehensive re-visit in mice.

Hon-Kan Yip, MD

Stem Cells Res Ther. 2022 Jun; 13(1): 265.
Dose-dependent benefits of iron-magnetic nanoparticle-coated human umbilical-derived mesenchymal stem cell treatment in rat intracranial hemorrhage model.

Pao-Yen Lin, MD PhD

J Affect Disord. 2022 Jan; 296: 609-615.
Comparative effectiveness of antidepressants on geriatric depression: Real-world evidence from a population-based study.

You-Lin Tain, MD

J Nutr Biochem. 2022 Oct; 108: 109090.
Sodium butyrate modulates blood pressure and gut microbiota in maternal tryptophan-free diet-induced hypertension rat offspring.

Chiung-Chih Chang, MD PhD

Neurotoxicology. 2022 Jan; 88: 178-186.
Comparisons of vesicular monoamine transporter type 2 signals in Parkinson’s disease and parkinsonism secondary to carbon monoxide poisoning.

Pei-Hsun Sung, MD

Biomed Pharmacother. 2022 Apr; 148: 112745.
Combined levosimendan and Sacubitril/Valsartan markedly protected the heart and kidney against cardiorenal syndrome in rat.

Kay L.H. Wu, PhD

Biomed J. 2022 Jun; 45(3): 491-503.
High fructose induced osteogenic differentiation of human valve interstitial cells via activating PI3K/AKT/mitochondria signaling.

Jenq-Lin Yang, PhD

Eur J Pharmacol. 2023 Jan; 938: 175439.
Oxidative DNA damage is concurrently repaired by base excision repair (BER) and apyrimidinic endonuclease 1 (APE1)‐initiated nonhomologous end joining (NHEJ) in cortical neurons.

Steve Leu, PhD

Biochem Pharmacol. 2021 Oct; 114672.
The role and regulation of Pnn in proliferative and non-dividing cells: Form embryogenesis to pathogenesis.

Ching-Yi Tsai, PhD

J Biomed Sci. 2022 July; 29(1):47.
Protective role of VEGF/VEGFR2 signaling against high fatality associated with hepatic encephalopathy via sustaining mitochondrial bioenergetics functions.

Kuang-Tzu Huang, PhD

Int J Mol Sci. 2022 Jan; 23(1): 256.
Emerging Roles of Calcium Signaling in the Development of Non-Alcoholic Fatty Liver Disease.

Ding-Wei Chen, PhD

J Invest Dermatol. 2021 Jul; S0022-202X(21)01457-3.
DNA Methylation Array Identifies Golli-MBP as a Biomarker for Disease Severity in Childhood Atopic Dermatitis.

Hong-Tai Tzeng, PhD

J Invest Dermatol. 2021 May; S0022-202X(21)01230-6.
Inhibition of PAI-1 Blocks PD-L1 Endocytosis and Improves the Response of Melanoma Cells to Immune Checkpoint Blockade.

Jei-Ming Peng, PhD

Cancer Lett. 2021 Jan; 497: 66-76.
CAMK2N1 suppresses hepatoma growth through inhibiting E2F1-mediated cell-cycle signaling.